Glucagonoma syndrome with atypical necrolytic migratory erythema
نویسندگان
چکیده
منابع مشابه
Glucagonoma syndrome associated with necrolytic migratory erythema.
INTRODUCTION glucagonoma is a pancreatic neuroendocrine tumor derived from alpha-cells of the islets of Langerhans. It is marked by tumoral autonomous production of glucagon and characterized, among other symptoms, by necrolytic migratory erythema, an erythematous circinate lesion with areas of necrosis and sloughing. This is a rare disease with worldwide incidence estimated at 1 case per 20 mi...
متن کاملGlucagonoma and necrolytic migratory erythema.
blood tests were normal except for glucose: 145 mg/dL. Baseline plasma glucagon levels were 1200 pg/mL. Serum zinc was 97 mcg/dL. An abdominal CT scan showed a large mass involving the body and tail of the pancreas. A distal pancreatectomy with splenectomy was performed and no evidence of metastatic disease was observed. The skin rash cleared within a week after the operation and the patient re...
متن کاملNecrolytic migratory erythema associated with glucagonoma syndrome: a case report.
Necrolytic migratory erythema is a rare skin condition that consists of migrating areas of erythema with blisters that heal with hyperpigmentation. It usually occurs in patients with an alpha islet cell tumor of the pancreas-or glucagonoma-and when associated with glucose intolerance, anemia, hyperglucagonemia, and weight loss defines the glucagonoma syndrome. We describe a 52-year-old female p...
متن کاملNecrolytic Migratory Erythema as the First Manifestation of Glucagonoma
Necrolytic migratory erythma (NME) as a rare skin disorder that can affected Perineum, distal extremities, lower abdomen and face are the most commonly affected sites.It can be as a part of Glucagonoma syndrome that is defined as an association of glucagonoma with NME, hyperglucagonemia, glucose intolerance, anemia and weight loss. Here, Authors describe a woman admitted to the dermatology ward...
متن کاملNecrolytic Migratory Erythema Associated with Glucagonoma: A Report of 2 Cases
Glucagonoma syndrome is a rare disease that is usually associated with an underlying neuroendocrine tumor. Necrolytic Migratory Erythema (NME) has been associated with intestinal malabsorption disorders, hepatic cirrhosis, chronic pancreatitis, inflammatory bowel disease, and non-pancreatic malignancies, but may not always be associated with glucagonoma. In 1979, Mallinson and co-workers coined...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology
سال: 2021
ISSN: 0378-6323
DOI: 10.4103/ijdvl.ijdvl_588_18